Dr. Joshua W. K. Ho

Laboratory Head


2004-2006 BSc (Hon 1, University Medal), Biochemistry and Computer Science, University of Sydney, Australia
2007-2010 PhD, Bioinformatics, University of Sydney, Australia

Academic appointment

2010-2012 Research Fellow in Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, USA
2012-2013 Instructor in Medicine (Genetics),Harvard Medical School and Brigham and Women's Hospital, Boston, USA
2013-present Laboratory Head at Victor Chang Cardiac Research Institute, Australia
2013-present Senior Lecturer (Conjoint) at University of New South Wales, Australia

Research Interest

  • Bioinformatics of next-generation sequencing
  • Systems biology approach to study embryonic development, gene regulatory networks
  • Chromatin-based epigenomics (ChIP-seq, DNase-seq...)
  • Whole genome/exome sequencing studies of human genetic diseases
  • Heart development and diseases
  • Software testing
  • Machine learning and data mining
  • Information visualization
  • Virtual reality in bioinformatics visualisation
  • Wearable devices signal analysis in cardiovascular diseases


  1. Ho JWK (2006) Computational Analysis of Evolution and Inference of Gene Regulatory Networks. BSc (Advanced) (Honours) Thesis, School of Biological Sciences, University of Sydney
  2. Ho JWK (2010) Principles and Applications of Bioinformatics for Systems Medicine. PhD Thesis, School of Information Technologies, University of Sydney


  • 2006 University Medal, The University of Sydney
  • 2007-2010 Australia Postgraduate Award and NICTA Research Project Award, The University of Sydney
  • 2009 Best paper award, International Conference on Quality Software 2009
  • 2014 Rod Rickards Fellowship (France-Australia Science Innovation Collaboration Program), Australian Academy of Science
  • 2015 NSW Ministerial Award for Rising Stars in Cardiovascular Research, Heart Foundation CVRN
  • 2015 Illumina Early Career Researcher Award, Australian Epigenetics Alliance
  • 2016-2019 NHMRC/National Heart Foundation Career Development Fellowship, NHMRC and Heart Foundation
  • 2016 Young Tall Poppy Science Award, Australian Institute of Policy and Science
  • 2017 Bioinformatics Peer Prize (link), The Thinkable Academy